What is Constella used for?
The medication Constella (linaclotide) is used to treat irritable bowel syndrome with constipation (IBS) in adults. The symptoms of IBS include abdominal pain, bloating, and altered bowel habits as well as long-term gut problems. It is also recommended for chronic idiopathic constipation (CIC) where the cause is not known. As part of Constella's active ingredient, the compound linaclotide binds to certain guanylate cyclase C receptors in the gut. These receptors are attached to the intestine and it increases intestinal fluid secretion by attaching to them. It is not recommended for individuals under 18 years of age as it has not been proven to be safe and effective.Constella (Linzess/Linaclotide) Information
How To Use Constella?
One capsule is recommended once a day with an empty stomach at least 30 minutes before your first meal of the day. It is important for doctors to assess the need for continued treatment on a periodic basis. Follow the instructions provided by your doctor and the medication guide included with the product.
You should swallow the capsules whole.
A reconsideration of the risks and benefits of continuing treatment should be undertaken if the patient has not experienced a significant improvement in symptoms after four weeks.
Taking Constella will reduce pain, bloating, and restore normal bowel function and feel less bloated. On the surface of your gut, guanylate cyclase C attaches to the drug and prevents it from entering your body.
The substance attaches to this receptor, blocking the sensation of pain and allowing liquid to enter the gut. This results in loose stools and more bowel movements.
Stored at room temperature away from children and animals when not in use. Report side effects and to your doctor or pharmacist if you find them manageable.
What are the common side effects of Constella?
Check with your doctor immediately if any of the following side effects of Constella occur:
- abdominal pain
- passing gas
- nausea
- diarrhea
- bloating (swelling or feeling of fullness in your abdomen)
- vomiting
There is a possibility that some people may experience side effects other than those listed here. During treatment with this medicine, you should consult your doctor if you experience any uncomfortable symptoms. Call your doctor for medical advice about side effects.
What are Drug Interactions of Constella?
Prescriptions, over the counter (non-prescription), herbal medicines, and over-the-counter medications should all be disclosed to your doctor or prescriber. Don't forget to mention any supplements you take. Caffeine, alcohol, and nicotine from cigarettes can interfere with the functioning of your medication. Tell your prescriber if you take any of these things.
The interaction between two medications does not always require stopping one. Check with your doctor if you are experiencing any drug interactions.
Do you need a prescription for Constella in Canada?
You do require a prescription to order Constella in Canada. Licensed pharmacies are unable to dispense prescription required drugs without one.
What is the recommended starting dose of Constella?
The recommended starting dose of Constella is 290 mcg once daily for irritable bowel syndrome with constipation (IBS-C) and 145 mcg once daily for chronic idiopathic constipation (CIC), though a lower dose of 72 mcg may be used if needed. It should be taken on an empty stomach, at least 30 minutes before breakfast.
Constella cost in Canada?
Starting price of Constella 72mcg cost in Canada
- 30 caps -Â $156.35 USD ($5.21 per caps)
- 60 caps -Â $285.50 USDÂ ($4.76 per caps)
- 90 caps -Â $392.60 USDÂ ($4.36 per caps)
Scroll up to see the specific pricing for each product, which is available in various strengths for both brand-name and generic options.
Constella (Linzess/Linaclotide) FAQs
Is Constella the same as Linzess?
Constella and Linzess are the same medication. They both contain the active ingredient linaclotide and are used to treat irritable bowel syndrome with constipation (IBS-C) and chronic idiopathic constipation (CIC). The name differs based on the country or region where the medication is sold.
How long does it take for Constella to work?
Constella (linaclotide) typically starts working within 1 to 2 days, but it may take up to a week for full effects. The time it takes to see improvement can vary from person to person, depending on factors like the severity of symptoms and individual response to the medication.
Can Constella cause diarrhea?
Yes, Constella (linaclotide) can cause diarrhea. It is one of the most common side effects of the medication. If diarrhea becomes severe or persistent, it’s important to contact your doctor. In some cases, adjusting the dose or stopping the medication may be necessary.
Does Constella cause dehydration?
Yes, Constella (linaclotide) can potentially cause dehydration, especially if it leads to severe diarrhea. Diarrhea can cause the body to lose fluids and electrolytes, which may result in dehydration. It’s important to stay hydrated and drink plenty of fluids while using Constella. If you experience symptoms of dehydration, such as dizziness, dry mouth, or reduced urination, you should contact your doctor.
Is Constella suitable for people with kidney or liver disease?
Constella may not be suitable for people with kidney or liver disease. It's important to consult with a healthcare provider before using Constella if you have any kidney or liver problems, as they can assess if it’s safe for you based on your specific condition. Always follow your doctor's advice when using any medication.