Constella (Linzess/Linaclotide)

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What is Constella used for?

The medication Constella (linaclotide) is used to treat irritable bowel syndrome with constipation (IBS) in adults. The symptoms of IBS include abdominal pain, bloating, and altered bowel habits as well as long-term gut problems. It is also recommended for chronic idiopathic constipation (CIC) where the cause is not known. As part of Constella's active ingredient, the compound linaclotide binds to certain guanylate cyclase C receptors in the gut. These receptors are attached to the intestine and it increases intestinal fluid secretion by attaching to them. It is not recommended for individuals under 18 years of age as it has not been proven to be safe and effective.

Constella (Linzess/Linaclotide) Information

How To Use Constella?

One capsule is recommended once a day with an empty stomach at least 30 minutes before your first meal of the day. It is important for doctors to assess the need for continued treatment on a periodic basis. Follow the instructions provided by your doctor and the medication guide included with the product.
You should swallow the capsules whole.

A reconsideration of the risks and benefits of continuing treatment should be undertaken if the patient has not experienced a significant improvement in symptoms after four weeks.

Taking Constella will reduce pain, bloating, and restore normal bowel function and feel less bloated. On the surface of your gut, guanylate cyclase C attaches to the drug and prevents it from entering your body.

The substance attaches to this receptor, blocking the sensation of pain and allowing liquid to enter the gut. This results in loose stools and more bowel movements.
Stored at room temperature away from children and animals when not in use. Report side effects and to your doctor or pharmacist if you find them manageable.

What are the common side effects of Constella?

Check with your doctor immediately if any of the following side effects of Constella occur:

  • abdominal pain
  • passing gas
  • nausea
  • diarrhea
  • bloating (swelling or feeling of fullness in your abdomen)
  • vomiting

There is a possibility that some people may experience side effects other than those listed here. During treatment with this medicine, you should consult your doctor if you experience any uncomfortable symptoms. Call your doctor for medical advice about side effects.

What are Drug Interactions of Constella?

Prescriptionsover the counter (non-prescription), herbal medicines, and over-the-counter medications should all be disclosed to your doctor or prescriber. Don't forget to mention any supplements you take. Caffeine, alcohol, and nicotine from cigarettes can interfere with the functioning of your medication. Tell your prescriber if you take any of these things.

The interaction between two medications does not always require stopping one. Check with your doctor if you are experiencing any drug interactions.

How much does Constella caps cost in Canada?

Starting price of Constella 72 mcg cost in Canada
- 90 caps - $372.00 USD ($4.13 per caps)

Generic options for this medication aren't available currently.

Please scroll up and refer to the products area for 72 mcg, 145 mcg, 290 mcg costs in Canada. Please check prices for your effect dose as the price may vary with strength.

Do you need a prescription for Constella in Canada?

You do require a prescription to order Constella in Canada. Licensed pharmacies are unable to dispense prescription required drugs without one.

Disclaimer: The information contained in this page is to provide basic information on this product and is not intended to substitute medical advice from a licensed doctor. Always make sure to consult with a doctor before ordering medication online from Canada. Do not avoid or delay seeing a healthcare provider based on what you read here.