Janumet XR (Sitagliptin – Metformin XR)

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What is Janumet XR prescribed for?

Janumet XR is prescribed to help manage blood sugar levels in people with type 2 diabetes. It combines two medications: metformin and sitagliptin, which work together to lower blood sugar and improve how your body uses insulin. It is usually used along with a healthy diet and exercise.

Janumet XR (Sitagliptin – Metformin XR) Information

How to use Janumet XR?

Take this medication by mouth as your doctor instructed, usually once a day with a meal, preferably in the evening.

Swallow the tablets whole. Do not crush or chew them, as this can cause too much of the medication to be released at once, increasing the chance of side effects.

Drink plenty of fluids while taking this medication unless your doctor tells you otherwise.

The dose you take depends on your medical condition, how you respond to the treatment, and any other medications you may be using.

Make sure to tell your doctor and pharmacist about all the medications you use, including prescription drugs, over-the-counter medicines, and herbal products.

To reduce side effects like an upset stomach, your doctor may start you on a low dose and then gradually increase it. Follow your doctor's instructions closely.

To get the most benefit, take your medication regularly. It helps to take it at the same time each day. Follow the treatment plan, meal plan, and exercise program your doctor has given you.

Let your doctor know if your condition does not improve or if it gets worse (if your blood sugar is too high or too low).

Before starting this medication and each time you refill it, read the Medication Guide and Patient Information Leaflet from your pharmacist. If you have any questions, ask your doctor or pharmacist.

Janumet XR drug interactions

The list provided below includes drugs that are recognized to interact with Janumet XR. However, it is important to note that this is not an exhaustive compilation of all potential drug interactions.

To stay safe and avoid problems, inform your doctor about all the medications you are currently using. This includes both prescribed medications and over-the-counter products. They will assess the potential interaction and determine whether it is beneficial to use both drugs together. If not, adjustments need to be made to your treatment plan

Common Side effects of Janumet XR?

Few known side effects of Janumet XR. Please note that this is not a complete list of all possible side effects of Janumet XR.

  • Diarrhea
  • Blurred vision
  • Rash
  • Sore throat
  • Stomach discomfort
  • Indigestion
  • Diabetes
  • Allergic reaction
  • Vomiting
  • Dizziness
  • Headache
  • Shallow breathing
  • Flatulence

If you encounter any indications or symptoms of severe side effects while taking this medication, it is important to consult your doctor or seek immediate medical attention.

Please inform your doctor about any side effects you experience. If you find these side effects difficult to manage, contact your doctor for medical advice.

What is the recommended starting dose of Janumet XR?

The recommended starting dose of Janumet XR is 100 mg of sitagliptin with 1,000 mg of metformin taken once daily with the evening meal. However, the dose may vary depending on your current treatment, kidney function, and how well you tolerate the medication. Your doctor will adjust the dose if needed.

How is Janumet XR different from regular Janumet?

Janumet XR is different from regular Janumet primarily because it is an extended-release version of the medication. This means that Janumet XR is designed to release its active ingredients slowly over time, allowing for once-daily dosing. In contrast, regular Janumet is taken twice daily. The extended-release formulation can provide more stable blood sugar control throughout the day and may improve convenience for patients by reducing the number of times they need to take their medication. Both versions contain the same active ingredients, but the way they are released into the body and the dosing schedule are what set them apart.

Who should not take Janumet XR?

Janumet XR should not be taken by individuals who are allergic to its ingredients, particularly sitagliptin or metformin. It is also not suitable for people with certain medical conditions, including severe kidney problems, liver disease, or a history of lactic acidosis.

Additionally, those who are experiencing diabetic ketoacidosis or have a serious infection should avoid using this medication. Pregnant or breastfeeding women should consult their doctor before taking Janumet XR.

Always talk to your healthcare provider to determine if this medication is right for you.

Janumet XR cost in Canada?

Starting price of Janumet XR 50mg/500mg cost in Canada

- 60 tabs - $146.90 USD ($2.45 per tab)
- 120 tabs - $283.40 USD ($2.36 per tab)
- 180 tabs - $392.60 USD ($2.18 per tab)

Scroll up to see the specific pricing for each product, which is available in various strengths for both brand-name and generic options.

Generic Equivalent Sitagliptin - Metformin XR cost in Canada?

Starting price of Generic Equivalent, Sitagliptin - Metformin XR 50mg/500mg cost in Canada

- 60 tabs - $138.50 USD ($2.31 per tab)
- 120 tabs - $256.10 USD ($2.13 per tab)
- 180 tabs - $370.55 USD ($2.06 per tab)

Scroll up to see the specific pricing for each product, which is available in various strengths for both brand-name and generic options.

Janumet XR (Sitagliptin – Metformin XR) FAQs

How long does it take for Janumet XR to start working?

Janumet XR usually starts working within a few hours after you take it. However, it might take a few days to notice its full effects on blood sugar levels. If you have any concerns about how it's working for you, it’s best to talk to your doctor.

How often should Janumet XR be taken?

Janumet XR is usually taken once a day. It's important to take it at the same time each day for the best results. Always follow your doctor’s instructions regarding dosage and timing.

How often should my blood sugar levels be checked while on Janumet XR?

While on Janumet XR, it’s generally recommended to check your blood sugar levels regularly. You should do this at least once a day, but your doctor may suggest checking it more often, especially if you're adjusting your dosage or experiencing symptoms. Always follow your healthcare provider's advice on how often to monitor your levels.

Disclaimer: The information provided here is intended as supplementary information to that provided by your doctor. The guidance provided by your doctor supersedes any information provided on the website. Do not avoid or disregard any counseling from your licensed medical professional based on this information. If you have any medical questions that are not answered here, we do offer counseling from a licensed pharmacist.