Sinemet (Carbidopa/Levodopa)

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What is Sinemet used for?

If you are suffering from Parkinson's disease, your doctor may prescribe this for you. Active ingredients of this drug include a carbidopa and levodopa combination. Decarboxylase inhibitors are among the indications for carbidopa, whereas dopamine precursors are among the indications for levodopa.

Sinemet (Carbidopa/Levodopa) FAQs

How To Use Sinemet?

Sinemet works by increasing the amount of dopamine in the brain, thus reducing Parkinson's disease symptoms. The recommended way to take the tablet (extended release) is by mouth. Your doctor will determine your dose based on a number of factors. Doctors usually start patients on a low dose and gradually increase it over time.

When starting Sinemet, your doctor may recommend taking one tablet of 10 mg carbidopa / 100 mg levodopa three to four times a day. However, the amount of carbidopa in this dose may not be sufficient to reduce your symptoms. You may be advised to take an extra 1/2 tablet every day or every other day. Your response to treatment may change your recommended dose.

It is important that you carefully read the Patient Information Leaflet. It is available from your pharmacist before you begin taking Sinemet.

What are the possible side effects of Sinemet?

The most commonly reported side effects of Sinemet include:

  • skin rash
  • headache
  • dizziness
  • cough
  • other cold symptoms
  • stuffy nose
  • blurred vision
  • diarrhea
  • nausea
  • muscle pain
  • drowsiness
  • constipation
  • itching
  • trouble sleeping (insomnia or strange dreams)
  • vomiting
  • dry mouth
  • sneezing
  • numbness or tingly feeling
  • heartburn
  • loss of appetite
  • High Blood Pressure
  • dark colored saliva, urine or sweat
  • difficulty falling asleep

There are other side effects that may occur that are not listed on this page.

Additional information about side effects can be obtained from your physician.

What are Drug Interactions of Sinemet?

Few known Drug Interactions of Sinemet are listed below:

  • Azilect (Rasagiline)
  • Vitamin B12 (Cyanocobalamin)
  • Gabapentin
  • Miralax (Polyethylene Glycol 3350)
  • Mirapex (Pramipexole)
  • Omeprazole
  • Lisinopril
  • Tylenol (Acetaminophen)
  • Clonazepam
  • Simvastatin
  • Lipitor (Atorvastatin)
  • Metformin
  • Aspirin Low Strength (Aspirin)
  • Vitamin D3 (Cholecalciferol)
  • Amantadine
  • Trazodone
  • Lasix (Furosemide)
  • Levothyroxine
  • Aspirin

A complete list of Sinemet Drug Interactions is not available on this page.

Call your doctor or pharmacist if you have any questions about this medicine's drug interactions.

How much does Sinemet cost in Canada?

Starting price of Sinemet 100mg/25mg cost in Canada
- 100 tabs - $130.00 USD ($1.30 per tabs)

Starting price of Sinemet 250mg/25mg cost in Canada
- 100 tabs - $140.00 USD ($1.40 per tabs)

How much is generic equivalent Levodopa/Carbidopa cost in Canada?

Starting price of Levodopa/Carbidopa 100mg/10mg cost in Canada
- 100 tabs - $34.00 USD ($0.34 per tabs)

Starting price of Levodopa/Carbidopa 100mg/25mg cost in Canada
- 100 tabs - $39.00 USD ($0.39 per tabs)

Starting price of Levodopa/carbidopa 250mg/25mg cost in Canada
- 100 tabs - $45.00 USD ($0.45 per tabs)

Do you need a prescription for Sinemet in Canada?

You do require a prescription to order Sinemet in Canada. Licensed pharmacies are unable to dispense prescription required drugs without one.

Disclaimer: The information contained in this page is to provide basic information on this product and is not intended to substitute medical advice from a licensed doctor. Always make sure to consult with a doctor before ordering medication online from Canada. Do not avoid or delay seeing a healthcare provider based on what you read here.