Synvisc One

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Synvisc One prescribed for?

Synvisc-One is prescribed to relieve knee pain caused by osteoarthritis. It’s usually recommended for people who haven’t gotten enough pain relief from other treatments like pain relievers, physical therapy, or exercise. Synvisc-One is injected directly into the knee joint, where it acts as a lubricant and cushion, helping the joint move more smoothly and reducing pain.

Synvisc One Information

How to use Synvisc One?

A healthcare professional will inject this medication directly into the affected joint, usually once a week, as prescribed by your doctor. The dose depends on your health and how you respond to treatment. Before the injection, any extra fluid in the joint may need to be removed.

Avoid using skin disinfectants with ammonium salts (like benzalkonium chloride) to clean the injection site, as they can interfere with the medication. Also, this medication should only be injected into the joint, not into a vein or artery, to prevent side effects.

After the injection, avoid putting stress on your knee for 48 hours. This includes activities like jogging, tennis, heavy lifting, or standing for over an hour. You might feel some pain or swelling in your knee initially, but if it gets worse or doesn’t improve, contact your doctor.
Be sure to get each injection as scheduled, as it may take up to three injections to feel the full benefits.

If available, read the Patient Information Leaflet from your healthcare provider before you start treatment and with each refill. If you have questions, ask your doctor or pharmacist, and let your doctor know if your symptoms don’t improve or get worse.

Synvisc One drug interactions

To stay safe and avoid problems always give your doctor a full list of all medications and supplements you take to avoid interactions. This includes both prescribed medications and over-the-counter products. They will assess the potential interaction and determine whether it is beneficial to use both drugs together. If not, adjustments need to be made to your treatment plan.

Common Side effects of Synvisc One?

Some known side effects of Synvisc One are listed below. Please note that this is not a complete list of all possible side effects of Synvisc One.

  • Flu
  • Warmth or swelling of the joints
  • Back pain
  • Nausea
  • Injection site pain
  • Fever or chills
  • Redness around the knee
  • Facial Flushing
  • Swelling of the knee
  • Fluid build-up in the joint
  • Itching
  • Headache
  • Difficulty walking
  • Injection site stiffness
  • Knee Pain
  • Dizziness

If you encounter any indications or symptoms of severe side effects while taking this medication, it is important to consult your doctor or seek immediate medical attention.

Please inform your doctor about any side effects you experience. If you find these side effects difficult to manage, contact your doctor for medical advice.

What is the recommended starting dose of Synvisc One?

The recommended starting dose of Synvisc-One is a single injection of 6 milliliters (mL) into the affected knee.

Synvisc One cost in Canada?

Starting price of Synvisc One 8mg/mL cost in Canada

- 6mL (1 Syringe x 6mL) - $506.00 USD ($84.33 per mL)
- 2 x 6mL (1 Syringe x 6mL) - $1007.90 USD ($83.99 per mL)
- 3 x 6mL (1 Syringe x 6mL) - $1501.40 USD ($83.41 per mL)

Scroll up to see the specific pricing for each product, which is available in various strengths for both brand-name and generic options.

Synvisc One FAQs

How long does the pain relief from Synvisc-One typically last?

The pain relief from Synvisc-One usually lasts about six months. However, some people may feel relief for a shorter or longer period, depending on their individual condition.

Can Synvisc-One be used for arthritis in joints other than the knee?

Synvisc-One is primarily approved for use in the knee joint to treat osteoarthritis pain. While some doctors may use it "off-label" in other joints, it’s best to consult your doctor to see if Synvisc-One is a suitable option for arthritis in joints other than the knee.

Do I need to prepare for a Synvisc-One injection in any way?

No special preparation is needed for a Synvisc-One injection. However, it can help to wear comfortable clothing that allows easy access to your knee, as the injection is usually given in a doctor’s office. Before the injection, your doctor may ask about any medications you’re taking to ensure there are no risks. Sometimes, they may drain any excess fluid from your knee before injecting Synvisc-One. You might want to arrange for a way home, as your knee could feel sore or stiff afterward, and it's a good idea to rest it for about 24 hours to allow the injection to settle in.

How soon after the injection can I resume normal activities?

You can usually resume normal activities right after a Synvisc-One injection. However, it's a good idea to avoid intense exercise or heavy activities for at least 48 hours to allow your joint to adjust. If you feel any soreness or swelling, rest and apply ice. If you have any concerns, it's best to follow up with your doctor.

Can Synvisc-One cause allergic reactions?

Yes, Synvisc-One can cause allergic reactions in some people, although it's rare. Symptoms of an allergic reaction may include redness, swelling, or itching at the injection site. If you notice any signs of an allergic reaction, contact your doctor immediately. Before getting the injection, make sure to inform your doctor about any allergies you have, especially to medications or substances like hyaluronate.

Disclaimer: The information provided here is intended as supplementary information to that provided by your doctor. The guidance provided by your doctor supersedes any information provided on the website. Do not avoid or disregard any counseling from your licensed medical professional based on this information. If you have any medical questions that are not answered here, we do offer counseling from a licensed pharmacist.