Temodal (Temozolomide)

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What is Temodal (Temozolomide) used for?

Temodal Capsule (Temozolomide) is used to treat certain cancers of the brain. It works by preventing cancer cells from creating DNA. It is used to treat brain tumors when they return or get worse after standard treatment. It may also be used to treat other conditions. If you are unsure what this is intended to treat, call your doctor for clarification. Temodal Capsule should be taken empty stomach and at same time each day to make sure it has the best effect. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. It is important to stick to their 28 day treatment cycle. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Temodal (Temozolomide) Information

How To Use Temodal (Temozolomide)?

Take this medication by mouth as directed by your doctor, usually once a day on a treatment schedule. Swallow the capsules whole with a full glass of water (8 ounces or 240 milliliters).

Do not crush, chew, or open the capsules. If you vomit after taking your dose, do not take any more medication. Wait and take your next dose at the regular time.

To reduce nausea and vomiting, take temozolomide on an empty stomach or at bedtime. For the best effect, take this medication at the same time every day in relation to a meal (for example, 1 hour before or 3 hours after a meal).

The dosage and treatment schedule are based on your medical condition, height, weight, and response to treatment. Carefully follow your doctor's directions for taking this medication. To help you remember, mark your calendar to keep track of when to take the next dose.

This medication can lower your white blood cell count. You may need to take precautions to avoid infections while taking this drug. Your doctor may also prescribe other medications (such as antibiotics) to help prevent infection or side effects. Follow your doctor's directions for taking all your medications.

Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster and your risk of serious side effects will increase.

If the capsules are accidentally opened or damaged, avoid contact with your skin or inhaling the medication. If contact occurs, flush the area with water. You should be screened for allergic reactions prior to treatment. Talk to your doctor or pharmacist if you experience an adverse reaction.

Since this drug can be absorbed through the skin and lungs and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle this medication or breathe the dust from the capsules.

What are the side effects of Temodal (Temozolomide)?

The most commonly reported side effects of Temodal (Temozolomide) include:

Less common or rare

  • Amnesia
  • black, tarry stools
  • blood in the urine or stools
  • convulsions
  • cough or hoarseness
  • fever or chills
  • lower back or side pain
  • muscle weakness or paralysis on one or both sides of the body
  • painful or difficult urination
  • pinpoint red spots on the skin
  • swelling of the feet or lower legs
  • unusual bleeding or bruising
  • Incidence not known
  • Abdominal or stomach pain or tenderness
  • blistering, peeling, or loosening of the skin
  • chest pain
  • clay colored stools
  • cough
  • decreased appetite
  • diarrhea
  • difficulty with swallowing
  • dizziness
  • fast heartbeat
  • headache
  • hives, itching, or skin rash
  • joint or muscle pain
  • nausea or vomiting
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • red skin lesions, often with a purple center
  • red, irritated eyes
  • sneezing
  • sore throat
  • sores, ulcers, or white spots in the mouth or on the lips
  • tightness in the chest
  • troubled breathing
  • unusual tiredness or weakness
  • yellow skin or eyes
  • hair loss

More common

  • Constipation
  • Less common or rare
  • Anxiety
  • blurred or double vision
  • breast pain (in females)
  • burning or prickling feeling on the skin
  • confusion
  • diarrhea
  • difficulty with speaking
  • drowsiness
  • increased urge to urinate
  • loss of appetite
  • loss of muscle coordination
  • mental depression
  • runny or stuffy nose
  • trouble sleeping

unusual weight gain

What are Drug Interactions of Temodal (Temozolomide)?

Few known Drug Interactions of Temodal (Temozolomide) are listed below.

  • Ativan (lorazepam)
  • Avastin (bevacizumab)
  • Bactrim (sulfamethoxazole / trimethoprim)
  • Bactrim DS (sulfamethoxazole / trimethoprim)
  • Benadryl (diphenhydramine)
  • Celebrex (celecoxib)
  • Colace (docusate)
  • Dilaudid (hydromorphone)
  • Keppra (levetiracetam)
  • Lasix (furosemide)
  • Lyrica (pregabalin)
  • MiraLAX (polyethylene glycol 3350)
  • Norco (acetaminophen / hydrocodone)
  • Paracetamol (acetaminophen)
  • Protonix (pantoprazole)
  • Synthroid (levothyroxine)
  • Tylenol (acetaminophen)
  • Vitamin B12 (cyanocobalamin)
  • Vitamin D3 (cholecalciferol)
  • Zofran (ondansetron)
  • Temozolomide

Disease interactions

There are 4 disease interactions with temozolomide which include:

  • urticaria
  • hepatic impairment
  • myelosuppression
  • renal impairment

How much does Temodal (Temozolomide) caps cost in Canada?

Starting price of Temodal 5mg cost in Canada
- 30 capsules - $336.00 USD ($11.20 per capsules)

Generic Equivalent Starting price of Temozolomide 5mg cost in Canada
- 15 capsules - $120.00 USD ($8.00 per capsules)

Please scroll up and refer to the product area for Temodal (Temozolomide) 5mg, 20mg, 100mg, 140mg, 250mg costs in Canada.

Do you need a prescription for Temodal (Temozolomide) in Canada?

You do require a prescription to order Temodal (Temozolomide) in Canada. Licensed pharmacies are unable to dispense prescription required drugs without one.

Disclaimer: The information provided here is intended as supplementary information to that provided by your doctor. The guidance provided by your doctor supersedes any information provided on the website. Do not avoid or disregard any counseling from your licensed medical professional based on this information. If you have any medical questions that are not answered here, we do offer counseling from a pharmacist.