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Wellbutrin XL (Bupropion)

What is Wellbutrin XL (Bupropion) used for?

There are several different types of Wellbutrin XL available on the market. Wellbutrin XL is prescribed for the treatment of major depression disorder, bipolar disorder, seasonal affective disorder, and smoking cessation. Depressive disorders can be treated with this medication. A type of depression that occurs every year at the same time (as in winter), seasonal affective disorder (SAD) may also be prevented through the use of this supplement. Several natural substances in the brain (dopamine, norepinephrine) may be restored when you take this medication.

Wellbutrin XL (Bupropion) Information

How To Use Wellbutrin XL (Bupropion)?

Your doctor will tell you whether you should take this medication with or without food, usually once a day in the morning. The medication can be taken with or after a meal or snack if you are experiencing stomach upset. The most benefit comes from taking this medication regularly and not taking it late in the day. When taking this medication late in the day, it may cause trouble sleeping (insomnia). To help you remember, take it at the same time each day.

Releasing the entire dose of bupropion from an extended-release tablet can cause side effects. Do not crush or chew extended-release tablets. Split the tablets only if your doctor or pharmacist says so or if there is a score line on them. It is best to swallow the whole tablet or split tablet whole, without crushing it or chewing it.

You will be prescribed a dosage based on the condition of your liver function and your response to the treatment. This medication may be prescribed at a low dose and gradually increased by your doctor to reduce the risk of side effects. The dose of this drug should not be increased or used more frequently or for a longer period than prescribed. You won't see an improvement in your condition any faster, and it'll increase the risk of side effects.

In some cases, your doctor may need to gradually decrease your dose of this medication. Do not suddenly stop taking bupropion without consulting your doctor. The full benefit of this drug may not be noticed for 4 weeks or more. Tell your doctor if your condition does not improve or worsens during this time.

What are the side effects of Wellbutrin XL (Bupropion)?

The most commonly reported side effects of Wellbutrin XL (Bupropion) include:

  • dry mouth
  • sore throat
  • nausea
  • vomiting
  • stomach/abdominal pain
  • flushing
  • headache
  • changes in appetite
  • weight loss or gain
  • constipation
  • trouble sleeping
  • increased sweating
  • increased urination
  • itching or skin rash
  • strange taste in mouth
  • joint aches
  • muscle pain
  • dizziness
  • ringing in your ears
  • loss of interest in sex
  • or blurred vision

Your doctor will weigh the risks and benefits of the drug before taking your first dose. Talk to your doctor for medical advice about side effects if you find them unmanageable.

Tell your doctor if you experience serious side effects of Wellbutrin XL including:

  • seizure (convulsions)
  • fast heartbeats
  • fever
  • swollen glands
  • rash or itching
  • joint pain
  • general ill feeling
  • confusion
  • trouble concentrating
  • hallucinations

Talk to your doctor if you have suicidal thoughts or behaviours, head injury, high blood pressure, heart disease or if you have an increased risk of seizures or heart attack.

What are Drug Interactions of Wellbutrin XL (Bupropion)?

Few known Drug Interactions of Wellbutrin XL (Bupropion) are listed below.

Wellbutrin XL disease interactions

There are 8 disease interactions with Wellbutrin XL (bupropion) which include:

  • suicidality
  • seizure disorders
  • angle closure glaucoma
  • liver disease
  • mixed/manic episode
  • psychosis
  • renal dysfunction
  • weight loss
  • eating disorder

What is the recommended starting dose of Wellbutrin XL (Bupropion)?

The recommended starting dose of Wellbutrin XL (Bupropion) is 150 mg once daily in the morning. If needed, the dose may be increased to 300 mg once daily after at least 3 days. The maximum recommended dose is 450 mg per day. Always follow your doctor's instructions to reduce the risk of side effects, such as insomnia or increased blood pressure.

Wellbutrin XL cost in Canada?

Starting price of Wellbutrin XL 150mg in Canada

- 90 tabs - $108.75 USD ($1.21 per tab)

Scroll up to see the specific pricing for each product, which is available in various strengths for both brand-name and generic options.

Generic Equivalent Bupropion cost in Canada?

Starting price of generic equivalent Bupropion SR 100mg cost in Canada

- 60 tabs - $64.50 USD ($1.08 per tab)
-120 tabs - $110.50 USD ($0.92 per tab)
- 180 tabs - $139.55 USD ($0.78 per tab)

Scroll up to see the specific pricing for each product, which is available in various strengths for both brand-name and generic options.

Wellbutrin XL (Bupropion) FAQs

How long does it take for Wellbutrin XL to start working?

Wellbutrin XL usually starts working within 1 to 2 weeks, but it may take 4 to 6 weeks to feel the full effects. Some people notice improved energy and motivation sooner, while mood changes may take longer.

Can Wellbutrin XL cause weight changes?

Yes, Wellbutrin XL can cause weight changes. Some people lose weight because it may reduce appetite, while others experience weight gain. However, weight loss is more common.

Does Wellbutrin XL cause sexual dysfunction?

Wellbutrin XL is less likely to cause sexual dysfunction compared to other antidepressants. In fact, some people may notice an improvement in libido and sexual function. However, individual reactions can vary.

What precautions should I take if I have a history of seizures?

If you have a history of seizures, talk to your doctor before taking Wellbutrin XL. This medication can lower the seizure threshold, increasing the risk of seizures. To reduce this risk:

- Avoid high doses and follow your doctor's prescription exactly.
- Do not drink alcohol or suddenly stop using alcohol or sedatives.
- Stay hydrated and maintain a balanced diet.
- Let your doctor know about any other medications you take, as some can increase seizure risk.

If you experience a seizure, stop taking Wellbutrin XL and seek medical help immediately.

Can Wellbutrin XL be used to treat seasonal affective disorder (SAD)?

Wellbutrin XL is approved to treat seasonal affective disorder (SAD). It can help prevent or manage depressive episodes that occur during seasonal changes, especially in fall and winter. Doctors may prescribe it before symptoms start and continue treatment through the season.

Disclaimer: The information provided here is intended as supplementary information to that provided by your doctor. The guidance provided by your doctor supersedes any information provided on the website. Do not avoid or disregard any counseling from your licensed medical professional based on this information. If you have any medical questions that are not answered here, we do offer counseling from a pharmacist.