Divigel 0.1% (Estradiol)

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What is Divigel used for?

Divigel is a medication that contains a female hormone called estrogen. It gets absorbed through the skin and goes into the bloodstream. Postmenopausal women use it to lessen a specific symptom of menopause, including hot flashes. During menopause, the body produces less estrogen, leading to these symptoms. This may not be safe for long term use increases the risk of developing cancer of the breast after 5 years.

Divigel 0.1% (Estradiol) Information

How to use Divigel?

Apply the medication to clean and dry skin on your upper thigh as your doctor directs, usually once a day. Switch between the right and left thigh each time you apply it.

Don't apply the medication to any broken or irritated skin. You should avoid using it on your breasts, face, or around the vagina.

Don't let anyone else apply the medication to your body.

The dosage is based on your medical condition and how you respond to the treatment. Never increase the dose or use it more often than prescribed.

After applying the medication, wash your hands thoroughly with soap and water to avoid spreading it accidentally to others. Let the application site dry completely before putting on clothes.

Wear clothes like shorts or pants to cover the area where you applied the medication, so others don't touch it. Wait at least 1 hour before allowing others to touch the skin where you applied the medication. If someone accidentally touches it within 1 hour, they should wash the area with soap and water immediately.

Wait 1 hour before showering or swimming for the medicine to absorb into your skin and work well.

Use the medication regularly at the same time each day to get the most benefit from it.

Avoid getting the medication in your eyes. If it happens, rinse your eyes with warm water and let your doctor know if you experience any eye irritation.

Before using the medication, read the Patient Information Leaflet if available from your pharmacist. Read it each time you get a refill. Make sure you know how to apply the gel correctly. If you have any questions, ask your doctor or pharmacist.

The medication is flammable until it's dry. So, make sure it's fully dry before smoking or going near an open flame.

If your condition doesn't improve or gets worse, tell your doctor. If you miss a dose you can take it when you remember. If it is almost time for your next dose you can skip the missed dose and continue with your schedule. Don't take an extra dose for make up for one that was missed.

Divigel drug interactions

The list provided below includes drugs that are recognized to interact with Divigel. However, it is important to note that this is not an exhaustive compilation of all potential drug interactions.

  • Singulair (Montelukast)
  • Tramadol
  • Trazodone
  • Lexapro (Escitalopram)
  • Xanax (Alprazolam)
  • Cyclobenzaprine
  • Tizanidine
  • Adderall (Amphetamine / Dextroamphetamine)
  • Albuterol
  • Pantoprazole
  • Turmeric
  • Amlodipine
  • Prednisone
  • Flonase (Fluticasone Nasal)
  • Meloxicam
  • Multivitamin
  • Clonazepam
  • Cymbalta (Duloxetine)
  • Zyrtec (Cetirizine)
  • Gabapentin
  • Levothyroxine
  • Omeprazole
  • Synthroid (Levothyroxine)
  • Metformin
  • Ibuprofen
  • Flexeril (Cyclobenzaprine)
  • Progesterone

To stay safe and avoid problems, inform your doctor about all the medications you are currently using. This includes both prescribed medications and over-the-counter products. They will assess the potential interaction and determine whether it is beneficial to use both drugs together. If not, adjustments need to be made to your treatment plan.

Common Side effects of Divigel?

Few known side effects of Divigel. Please note that this is not a complete list of all possible side effects of Divigel

  • nausea
  • swollen breasts
  • vaginal itching or discharge
  • dizziness
  • depression
  • vomiting
  • migraine headaches
  • acne or skin color changes
  • difficulty having an orgasm
  • swelling
  • decreased sex drive
  • break-through bleeding
  • weight gain
  • vaginal pain/dryness/discomfort
  • loss of appetite
  • high blood pressure
  • breast tenderness

If you experience severe side effects while taking this medicine, it is crucial to seek immediate medical attention from your doctor. Talk to your doctor if you experience abdominal pain, stroke or blood clot. Report any unusual vaginal bleeding.

Please inform your doctor about any side effects you experience. If you find these side effects difficult to manage, contact your doctor for medical advice.

Divigel 0.1% (Estradiol) FAQs

Divigel Sachets cost in Canada?

Divigel 0.1% 0.25mg sachets cost in Canada

- 30 sachets - $57.75 USD ($1.93 per sachets)

- 60 sachets - $100.80 USD ($1.68 per sachets)

- 90 sachets - $124.58 USD ($1.38 per sachets)

Can men use Divigel?

No, men should not use Divigel. But In some cases, Divigel may be used in men who are undergoing androgen deprivation therapy for prostate cancer. However, this is only done under the supervision of a doctor and with careful monitoring of the patient's hormone levels.

If you are a man and are considering using Divigel, you should talk to your doctor first. They can help you determine if Divigel is right for you and can discuss the potential risks and benefits.

How does Divigel work to relieve menopausal symptoms?

Divigel works by delivering estrogen, a hormone that helps relieve menopausal symptoms. When menopause occurs, a woman's ovaries produce less estrogen, leading to symptoms like hot flashes and vaginal dryness. Divigel is a gel that contains estrogen, and when applied to the skin, it gets absorbed into the bloodstream. The estrogen then helps balance hormonal levels, reducing menopausal symptoms and making women feel better.

Can I use Divigel if I have had a hysterectomy?

If you've had your uterus removed (hysterectomy), then the likely answer is no. After the surgery, your doctor may suggest that you take estrogen therapy without progestin.

How long does it take for Divigel to start working?

Divigel usually starts working within a few weeks of consistent use. Divigel significantly reduced almost 90% of hot flashes within 12 weeks. Even in as little as 2 weeks it cut the number of hot flashes by nearly half.

However, the exact time frame can vary from person to person. It's essential to follow your doctor's instructions and be patient while waiting for the effects to take place. If you have any concerns or questions, always consult your healthcare provider.

Can Divigel be used to prevent osteoporosis?

No, Divigel is not used to prevent osteoporosis. It is a medication containing estradiol, which is a form of estrogen used to treat menopausal symptoms in women. To prevent osteoporosis, other medications and lifestyle changes are typically recommended. If you have any concerns or questions, always consult your healthcare provider.

Can Divigel be used as a form of birth control?

No, Divigel cannot be used as a form of birth control. It is a topical gel that contains the hormone estradiol, which is used to treat symptoms of menopause in women. It does not provide contraception or prevent pregnancy. If you are looking for birth control options, you should speak with a healthcare professional to discuss suitable methods.

What should I do if I accidentally overdose on Divigel?

If you accidentally overdose on Divigel, seek immediate medical help. Call emergency services or go to the nearest hospital right away. It's crucial to get professional medical attention to ensure your safety and receive the appropriate treatment for the overdose.

Can Divigel be used to treat other conditions besides menopausal symptoms?

No, Divigel is mainly used to treat menopausal symptoms and is not recommended for treating other conditions. If you have any concerns or questions, always consult your healthcare provider.

Disclaimer: The information provided here is intended as supplementary information to that provided by your doctor. The guidance provided by your doctor supersedes any information provided on the website. Do not avoid or disregard any counseling from your licensed medical professional based on this information. If you have any medical questions that are not answered here, we do offer counseling from a licensed pharmacist.