Sprycel (Dasatinib)

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What is Sprycel (Dasatinib) prescribed for?

Sprycel (dasatinib) is a targeted cancer drug that is prescribed to treat chronic myeloid leukemia (CML) and acute lymphoblastic leukemia (ALL). In combination with chemotherapy It works by blocking the activity of certain proteins on types of cancer cells. This slows or stops their growth.

Sprycel (Dasatinib) Information

How to use Sprycel?

Take dasatinib by mouth as directed by your doctor. You can take it with or without food, once a day.

Swallow the tablets whole and do not crush, chew, or break them.

The dosage will depend on your condition, response to treatment, lab test results, and other medications you're taking. If giving dasatinib to a child, the dosage is based on their weight.

Inform your doctor and pharmacist about all the products you use, including prescription drugs, over-the-counter drugs, and herbal products. Do not increase the dose or use the medicine more frequently or for a longer period than prescribed.

Avoid taking antacids within 2 hours before or after taking this medicine, as they can interfere with its absorption. Avoid consuming grapefruit or grapefruit juice while taking this medicine, as it can increase the risk of side effects.

Avoid handling the medicine or inhaling the dust from the tablets If you're pregnant or may become pregnant. It may harm an unborn baby.

Read the Patient Information Leaflet provided by your pharmacist before starting dasatinib or getting a refill. Ask your doctor or pharmacist if you have any questions.

Sprycel drug interactions

The list provided below includes drugs that are recognized to interact with Sprycel. However, it is important to note that this is not an exhaustive compilation of all potential drug interactions.

Disclose all of your current medications, including prescription medications and OTC products, to your doctor. They will assess the potential interaction and determine whether it is beneficial to use both drugs together. If not, adjustments need to be made to your treatment plan.

Common Side effects of Sprycel?

Few known side effects of Sprycel Tabs. Please note that this is not a complete list of all possible side effects of Sprycel.

  • upset stomach
  • weight loss
  • body aches
  • vomiting
  • flu-like symptoms
  • weakness
  • muscle and joint pain or discomfort
  • mouth sores
  • nausea
  • diarrhea
  • headaches
  • constipation
  • mild skin rash
  • tired feeling
  • loss of appetite

Inform your doctor if you have side effects that include fluid retention, swelling and pain in the ankles and joints, dry cough and chest pain.

What is the recommended starting dose of Sprycel?

The starting dose of Sprycel (dasatinib) depends on the condition being treated. For chronic-phase chronic myeloid leukemia (CP-CML), the usual starting dose is 100 mg once daily. For more advanced phases of CML or Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL), the starting dose is 140 mg once daily.

Sprycel should be taken as a whole tablet, with or without food. Avoid grapefruit and grapefruit juice, as they can interfere with the medication. Doses may be adjusted based on how well you tolerate the drug and your response to treatment. Always follow your doctor’s instructions for the best results.

Sprycel cost in Canada?

Starting price of Sprycel 20mg cost in Canada
- 60 tabs - $2996.50 USD ($49.94 per tab)
- 120 tabs - $5970.00 USD ($49.75 per tab)
- 180 tabs - $8889.50 USD ($49.39 per tab)

Scroll up to see the specific pricing for each product, which is available in various strengths for both brand-name and generic options.

Generic Equivalent Dasatinib cost in Canada?

Starting price of Dasatinib 20mg cost in Canada
- 30 tabs - $989.00 USD ($32.97 per tab)
- 60 tabs - $1965.50 USD ($32.76 per tab)
- 90 tabs - $2931.50 USD ($32.57 per tab)

Scroll up to see the specific pricing for each product, which is available in various strengths for both brand-name and generic options.

Sprycel (Dasatinib) FAQs

What should I discuss with my doctor before starting Sprycel?

Before starting Sprycel, it's important to talk to your doctor about your medical history. This includes allergies, medications, pregnancy, pre-existing conditions, side effects, and other treatments.

Your doctor will help you understand the risks and benefits of taking Sprycel. It is important to have a detailed conversation with your doctor. You can make an informed decision about whether or not to start Sprycel.

How often do I need to have blood tests while taking Sprycel?

The frequency of blood tests will depend on your doctor's recommendations and your individual situation. You will need blood tests more often at the beginning of treatment, and then less often as your treatment stabilizes. It's important to follow your doctor's instructions and communicate with them about your treatment plan.

Are there any monitoring or testing requirements while on Sprycel?

While taking Sprycel, you need to have regular blood tests and other tests to make sure the medication is working. These tests may include blood cell counts, liver function tests, and electrolyte levels. You may also need to have cardiac monitoring tests to check your heart function. It is important to follow your healthcare provider's instructions for these tests to ensure safe and effective use of Sprycel.

How quickly does Sprycel start working?

Sprycel (dasatinib) typically starts working within a few days to weeks, but it can take a few months to see the full effects. The exact response time can vary depending on the individual and the condition being treated. It's important to follow your doctor's guidance and attend regular check-ups to monitor progress.

Is Sprycel safe for children?

Sprycel (dasatinib) is not typically recommended for children unless prescribed by a doctor. It is sometimes used to treat certain types of leukemia in children, but only under close medical supervision. The safety and dosage for children depend on their age, weight, and specific health condition, so it's important to follow the doctor's instructions carefully. Always consult a healthcare provider before using Sprycel for a child.

Can Sprycel cause fatigue?

Yes, Sprycel (dasatinib) can cause fatigue as a side effect. Fatigue is a common issue for people taking Sprycel, along with other side effects like nausea, headache, and muscle pain. If fatigue becomes severe or affects daily life, it's important to talk to a doctor, as they may adjust the dosage or suggest ways to manage the side effect.

Disclaimer: The information provided here is intended as supplementary information to that provided by your doctor. The guidance provided by your doctor supersedes any information provided on the website. Do not avoid or disregard any counseling from your licensed medical professional based on this information. If you have any medical questions that are not answered here, we do offer counseling from a licensed pharmacist.