What is Xeljanz (Tofacitinib) prescribed for?
Xeljanz is a prescription medicine used to treat the symptoms of moderately to severely active Rheumatoid Arthritis, Psoriatic Arthritis, and active Ulcerative Colitis. Xeljanz may be used alone or with other medications. Xeljanz belongs to a class of drugs called DMARDs, Immunomodulators; DMARDs, JAK Inhibitors. Xeljanz may lower your white blood cell's ability to fight infections. This may make you more likely to get a serious (rarely fatal) infection or make any infection you have worse. Tell your doctor right away if you have any signs of infection including sore throat that doesn't go away, fever, chills, cough, trouble breathing, painful/frequent urination, non-healing skin sores).
Xeljanz (Tofacitinib) Information
How To Use Xeljanz?
Take this medication by mouth with or without food as directed by the medication guide and your doctor, usually once or twice daily.
If you are using the liquid form of this medication, carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.
The dosage is based on your medical condition, response to treatment, lab tests, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
Children's dosage is also based on weight. Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of serious side effects will increase.
Take this medication regularly to get the most benefit from it. Remember to take it at the same time(s) each day.
Tell your doctor if your condition does not get better or if it gets worse. If you are 50 years of age or older you may have an increased risk of cardiovascular events. Since it makes it harder for your immune system to fight infections, you may have a higher risk of tuberculosis (TB) and fungal infections.
Seek immediate medical attention if you experience an allergic reaction.
What are Drug Interactions of Xeljanz?
Few known Drug Interactions of Xeljanz are listed below:
- Lyrica (Pregabalin)
- Tramadol
- Lisinopril
- Gabapentin
- Metformin
- Levothyroxine
- Vitamin D3 (Cholecalciferol)
- Prednisone
- Cymbalta (Duloxetine)
- Amlodipine
- Plaquenil (Hydroxychloroquine)
- Omeprazole
- Pantoprazole
- Methotrexate
- Meloxicam
- Atorvastatin
- Losartan
- Folic Acid
- Vitamin B12 (Cyanocobalamin)
A complete list of Xeljanz Drug Interactions is not available on this page.
Consult your physician if you have any questions about this medicine's drug interactions.
What are the possible side effects of Xeljanz?
Xeljanz may cause serious side effects including:
- heavy sweating
- mouth sores
- shortness of breath
- weight loss
- lightheadedness
- cough with pink or red mucus
- burning pain
- fever
- feeling very tired
- dark urine
- cold hands and feet
- stomach pain
- pale skin
- sweating
- pain, swelling, or redness in an arm or a leg
- loss of appetite
- chills
- yellowing of the skin or eyes (jaundice)
- itching
- pain or burning when you urinate
There are other side effects that may occur that are not listed on this page.
Additional information about side effects can be obtained from your physician.
What are the recommended dosages of Xeljanz?
The recommended dosage of Xeljanz (tofacitinib) varies depending on the condition being treated. For rheumatoid arthritis (RA) and psoriatic arthritis (PsA), the usual dose is 5 mg taken twice a day, or 11 mg once a day for the extended-release tablet. For ulcerative colitis, the typical starting dose is 10 mg twice a day for at least 8 weeks, followed by 5 mg twice a day. However, the dosage may need to be adjusted for people with kidney or liver issues or those taking certain medications. It's important to follow your doctor's instructions carefully and to communicate any concerns or side affects you may experience while taking Xeljanz. Only your healthcare provider can determine the appropriate dosage for your specific condition.
Generic equivalent Tofacitinib cost in Canada?
Tofacitinib 5mg tabs cost in Canada
- 60 tabs - $402.00 USD ($6.70 per tab)
- 120 tabs - $782.00 USD ($6.52 per tab)
- 180 tabs - $1,142.00 USD ($6.34 per tab)
Xeljanz cost in Canada?
Xeljanz 5mg tabs cost in Canada
- 60 tabs - $1,932.00 USD ($32.20 per tab)
- 120 tabs - $3,728.00 USD ($31.07 per tab)
- 180 tabs - $5,291.00 USD ($29.39 per tab)
Xeljanz (Tofacitinib) FAQs
Does Xeljanz cause weight gain?
Xeljanz do not cause people to gain weight as a side effect. But, some serious side effects from these medicines or your health issues might make you lose weight unexpectedly. For example, if you have diarrhoea, a bad infection, you might lose weight.
How long does it take for Xeljanz to start working?
Xeljanz typically starts working within a few weeks to a few months after you begin taking it. The exact timeframe can vary from person to person. It's important to follow your doctor's instructions and continue taking the medication as prescribed even if you don't see immediate results. If you have any concerns or questions about the effectiveness of Xeljanz, it's best to discuss them with your healthcare provider.
Does Xeljanz affect the immune system?
Yes, Xeljanz can affect the immune system. It works by slowing down certain parts of the immune response. This can help in treating certain conditions, but it might also increase the risk of infections. Your doctor will monitor this while you're on the medication.
Can Xeljanz be used with biologic therapies?
Using Xeljanz with biologic therapies is generally not recommended. Combining these treatments can increase the risk of infections and other side effects. It's important to discuss your specific situation with your doctor before making any decisions about your treatment plan. They will help determine the best approach for your health.
Can Xeljanz be used in patients with liver or kidney problems?
Xeljanz may not be suitable for patients with severe liver or kidney problems. Before starting Xeljanz, it's crucial to discuss your medical history and any existing liver or kidney conditions with your doctor. They will evaluate whether the medication is safe and appropriate for you or not, considering your specific health condition.