What is Parnate (Tranylcypromine) prescribed for?
Tranylcypromine, commonly known as Parnate, is prescribed for treating the symptoms of Major Depressive Disorder. There are several medications that can be used together or in conjunction with Parnate. The safety and effectiveness of Parnate in children is unknown. A monoamine oxidase inhibitor (MAOIS), Parnate is utilized to treat depression. Depression is treated with this medication by restoring the balance of certain brain chemicals (neurotransmitters). You can feel better and your mood can improve when you take parnate.
Parnate (Tranylcypromine) Information
How To Use Parnate (Tranylcypromine)?
The medication should be taken by mouth, normally in divided doses according to your doctor's instructions. A dose of this medication is usually not more than 60 milligrams per day. Your dose depends on your medical condition and response to therapy. It may be taken with or without food.
Starting at a low dosage and gradually increasing it may reduce your risk of side effects. You may be able to reduce your regular dose once your condition improves and you feel better for a while. Be sure not to take more or less medication than prescribed.
Follow your doctor's instructions and the medication guide carefully. if you take more than your recommended dose your condition will not improve. You may have an increased risk of side effects.
Taking this medication regularly will help you to get the most benefit. Make sure you take it at the same time( each day to keep yourself from forgetting. If you are taking this medication, you may not notice the full benefits for several weeks. Call your doctor before you stop taking tranylcypromine.
This medication may cause withdrawal symptoms (such as restlessness, confusion, hallucinations, headaches, weakness, and diarrhea) if you suddenly stop using it. It may be necessary for your doctor to lower your dose slowly in order to prevent withdrawal symptoms. In the event of withdrawal, tell your doctor or pharmacist as soon as possible. If you have been using tranylcypromine for long or at a high dosage, you are more likely to experience withdrawal symptoms.
Please notify your physician if your condition worsens or lasts for an extended period of time.
What are the possible side effects of Parnate (Tranylcypromine)?
The most commonly reported side effects of (Tranylcypromine) include:
- difficulty breathing
- sudden and severe headache
- mood or behavior changes
- loss of appetite
- dilated pupils
- irritableness
- being agitated or talkative
- hallucinations
- restlessness
- numbness or weakness
- impulsiveness
- risk-taking behavior
- loss of coordination
- hyperactivity (mentally or physically)
- hives
- aggression
- fast or pounding heartbeats
- anxiety
- muscle stiffness
- panic attacks
- twitching
- sweating
- racing thoughts
- increased energy
- trouble sleeping
- increased depression
- throughs about suicide
- neck pain or stiffness
- seizures
- vision problems
- vomiting
There are other side effects that may occur that are not listed on this page. Call your doctor for medical advice about side effects if you find them unmanageable.
Talk to your doctor if you experience adverse effects including high blood pressure, liver problems or hypertensive crisis. You should not drink alcohol while taking this product.
What are Drug Interactions of Parnate (Tranylcypromine)?
Few known Drug Interactions of Parnate (Tranylcypromine) are listed below:
- Klonopin (Clonazepam)
- Xanax (Alprazolam)
- Nardil (Phenelzine)
- Trazodone
- Vitamin D3 (Cholecalciferol)
- Lithium Carbonate Er (Lithium)
- Prozac (Fluoxetine)
- Seroquel (Quetiapine)
- Cymbalta (Duloxetine)
- Gabapentin
- Adderall (Amphetamine / Dextroamphetamine)
- Lamictal (Lamotrigine)
- Lamotrigine
- Lithium
- Omeprazole
- Synthroid (Levothyroxine)
- Abilify (Aripiprazole)
- Ritalin (Methylphenidate)
- Clonazepam
A complete list of Parnate (Tranylcypromine) Drug Interactions is not available on this page.
Consult your physician if you have any questions about this medicine's drug interactions.
What is the recommended starting dose of Parnate (Tranylcypromine)?
The recommended starting dose of Parnate (Tranylcypromine) is 30 mg per day, typically divided into two doses of 15 mg each. If necessary, the dose can be increased gradually in increments of 10 mg per day every 1 to 3 weeks, with a usual maximum dose of 60 mg per day. However, dosing should always be guided by a healthcare professional based on the patient's response and tolerance.
Parnate cost in Canada?
Starting price of Parnate 10mg in Canada
- 100 tabs - $98.25 USD ($0.98 per tab)
- 200 tabs - $167.25 USD ($0.84 per tab)
- 300 tabs - $221.25 USD ($0.74 per tab)
Scroll up to see the specific pricing for each product, which is available in various strengths for both brand-name and generic options.
Parnate (Tranylcypromine) FAQs
How long does Parnate take to start working?
Parnate (tranylcypromine) usually starts working within 2 to 4 weeks. Some people may notice improvements in mood and energy earlier, but full effects can take up to 6 weeks.
Can Parnate be used for anxiety?
Parnate is primarily used to treat depression, but it may help with anxiety in some cases, especially if it's linked to depression. However, it can also make anxiety worse in some people. Always consult a doctor to see if it's right for you.
How effective is Parnate for depression?
Parnate is considered highly effective for depression, especially for people who don’t respond well to other antidepressants. It is particularly useful for treating major depressive disorder and atypical depression. However, its effectiveness varies by person, and it has dietary and medication restrictions.
How long does Parnate stay in your system?
Parnate (tranylcypromine) has a half-life of about 2 to 3 hours, but its effects last much longer because it irreversibly inhibits MAO enzymes. It can take up to 10 days for the body to fully restore MAO activity after stopping the medication.
Can Parnate cause serotonin syndrome?
Parnate may cause serotonin syndrome, especially if taken with other medications that increase serotonin, such as SSRIs, SNRIs, TCAs, or certain pain medications. Serotonin syndrome is a serious condition that can cause confusion, fever, sweating, rapid heart rate, and muscle stiffness. Always consult a doctor before combining medications.