Premarin Vaginal Cream (conjugated estrogens vaginal cream)

Follow your doctor's instructions when using this medication. Fill the applicator with the medication according to the provided directions. Place the applicator high into the vagina and push the plunger to release the medication.

Clean the applicator using warm soapy water and rinse it thoroughly. Avoid boiling or using hot water to clean the applicator.

The dosage of this medication depends on your medical condition and how you respond to treatment.

To gain the most benefit from this medication, use it regularly. Stick to your prescribed dosing schedule. Do not increase your dose or use this medication more frequently or for a longer duration than directed.

Before starting to use this medication read the Patient Information Leaflet if it is available from your pharmacist. If you have any questions, consult your doctor or pharmacist.

Inform your doctor if your condition does not improve or if it gets worse.

The list provided below includes drugs that are recognized to interact with Premarin Vaginal Cream. However, it is important to note that this is not an exhaustive compilation of all potential drug interactions.

• Aspirin Low Strength (Aspirin)
• Zyrtec (Cetirizine)
• Vitamin C (Ascorbic Acid)
• Omeprazole
• Prednisone
• Hydrochlorothiazide
• Tramadol
• Magnesium Oxide
• Simvastatin
• Amlodipine
• Gabapentin
• Synthroid (Levothyroxine)
• Melatonin
• Atorvastatin
• Losartan
• Metformin
• Pantoprazole
• Biotin
• Flonase (Fluticasone Nasal)
• Cymbalta (Duloxetine)
• Fish Oil (Omega-3 Polyunsaturated Fatty Acids)
• Lisinopril
• Trazodone
• Albuterol
• Tylenol (Acetaminophen)

Disclose all of your current medications, including prescription medications and OTC products, to your doctor. They will assess the potential interaction and determine whether it is beneficial to use both drugs together. If not, adjustments need to be made to your treatment plan.

Few known side effects of Premarin Vaginal Cream. Please note that this is not a complete list of all possible side effects of Premarin Vaginal Cream.

• feeling of warmth or heat
• lower back or side pain
• Feeling faint, dizzy, or lightheaded
• change in vaginal discharge
• sweating
• increased clear or white vaginal discharge
• headache
• painful or difficult urination
• pain or feeling of pressure in the pelvis
• itching of the vagina or genital area
• vaginal bleeding
• flushing or redness of the skin, especially on the face and neck
• breast pain
• pain during sexual intercourse
• cough or hoarseness
• fever or chills
• high blood pressure

Seek immediate medical attention if you experience serious reactions including unusual vaginal bleeding, shortness of breath or an allergic reaction. Advise your doctor if you have an increased risk of liver disease strokes or dementia.

Please inform your doctor about any side effects you experience. If you find these side effects difficult to manage, contact your doctor for medical advice.

The recommended dosage of Premarin Vaginal Cream can vary depending on the specific condition being treated. It is important to follow the instructions provided by your doctor or pharmacist.

The usual starting dose for the treatment of menopausal symptoms is determined by your doctor. A small amount of cream is applied inside the vagina once daily for the first few weeks.

After that, the dosage may be reduced to two or three times per week. It's important to note that individual dosages may vary. It's best to consult your healthcare professional for specific guidance on how to use Premarin Vaginal Cream.